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🤯 New ChatGPT 'o1' models push AI to PhD-level intelligence

ALSO: Apple turns AirPods into hearing aids and Adds sleep apnea detection to watch, Making tissues transparent: a breakthrough in medical imaging?, Polaris Dawn embarks on first private civilian spacewalk to advance health research

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“ChatGPT-3 was toddler-level, GPT-4 was a smart high schooler, and the next gen, to be released in a year and a half, will be PhD-level.” These were the words of Mira Murati, CTO of OpenAI, just three months ago. Yesterday, OpenAI defied expectations, releasing two new models capable of human-like reasoning far sooner than anticipated.

Are we already entering the age of doctor-level AI?

Let’s dive in!

Victor

TODAY’S MENU

  • OpenAI’s New ‘o1’ Models Push AI to PhD-Level Intelligence

  • Apple Turns AirPods Into Hearing Aids and Adds Sleep Apnea Detection to Watch

  • Making Tissues Transparent: A Breakthrough in Medical Imaging?

  • Polaris Dawn: A Historic Spacewalk Serving Medical Science

  • Neuroscientists Map How the Brain Transforms Sensation into Action

  • Everything Else You Should Know this Week

    Read time: under 7 minutes

CHATBOT

Credit: OpenAI

OpenAI’s long-rumored ‘strawberry’ models have finally ripened, and the wait seems worth it! The newly released o1 and o1-mini models are designed to solve complex problems in science, coding, and math, offering invaluable tools for healthcare professionals and researchers.

Key Insights:

  • The o1 models take a more thoughtful approach, refining their problem-solving processes like a human, and outperforming earlier models in fields such as physics, chemistry, and biology.

  • They scored 83% on the International Mathematics Olympiad qualifying exam, compared to 13% for GPT-4o.

  • Use cases include healthcare researchers annotating cell-sequencing data and physicists generating mathematical formulas for quantum optics.

Is there a trade-off? It’s bit slow. OpenAI claims the model will take its time before responding to prompts. The new models also lack some of the capabilities that GPT-4o has, like web browsing and file uploads.

When can I use it? If you have a subscription to ChatGPT Plus or Enterprise, you can already access these new models. Simply pick it in the dropdown menu on the top of your screen in ChatGPT.

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WEARABLES

Credit: Apple

During its latest keynote, Apple announced two major healthcare features: AirPods Pro 2 will double as over-the-counter hearing aids, and the Apple Watch will soon detect sleep apnea, a condition affecting 25 million Americans.

Key Details:

  • AirPods Pro 2 will offer real-time hearing aid functionality for mild to moderate hearing loss, using machine learning to adjust sound. A clinical-grade hearing test will also be available, making hearing health more accessible to millions.

  • Apple Watch will track breathing disturbances to detect sleep apnea using an accelerometer, alerting users to moderate or severe apnea. Data will be securely shared with healthcare providers for follow-up.

Why It Matters: While FDA clearance is still pending for sleep apnea detection, these updates could make hearing aids and sleep apnea screening more accessible for millions. With this move, Apple sparks important conversations about integrating wearables into clinical care.

STUDY

A recent study may revolutionize the way we see inside the human body. Scientists have developed a new approach to making biological tissues transparent by using dye molecules like tartrazine (a common food colorant). While it might seem counterintuitive, these molecules absorb light in certain regions, which helps make tissues like skin and muscles transparent at other wavelengths. The result? Clearer images of internal organs and tissues without the need for invasive surgery.

Why It Matters: This technique, tested on live rodents, enabled scientists to visualize internal structures like neurons and blood vessels with incredible precision. If someday applied to humans, it could transform medical imaging, allowing doctors to better monitor organs and detect diseases without surgery.

SPACEX

Early Tuesday morning, SpaceX’s Dragon capsule launched as part of the Polaris Dawn mission, carrying four civilian crew members on a groundbreaking spacewalk. Beyond space exploration, the mission is focused on studying human biology and space health, gathering critical data on the body’s response to spaceflight.

The Details

  • Researchers are studying early cancer detection by tracking biomarkers for radiation exposure, aiming to uncover early signs of carcinogenesis.

  • Novel 3D scanning technology is being used to monitor body morphology, tracking changes in water, fat, and muscle distribution during spaceflight.

  • The mission also focuses on collecting biomedical data to assess the psychological and cognitive impacts of space on human health.

  • Polaris Dawn will contribute its findings to NASA and TRISH’s EXPAND database, helping researchers study diverse health profiles and responses to space environments.

Why It Matters: This mission offers invaluable insights into how the human body adapts to the unique stresses of space, paving the way for safer long-term space exploration to the Moon and Mars. Additionally, data from Polaris Dawn may lead to breakthroughs in healthcare on Earth, including non-invasive diagnostic tools.

NEUROSCIENCE

A new study by researchers at the Sainsbury Wellcome Center (UCL) reveals how the brain transforms sensory input into motor action, coordinated across multiple regions. Using cutting-edge Neuropixels probes, the team recorded neural activity across 52 brain regions in mice during decision-making tasks.

Key Insights:

  • Mice were trained to detect changes in visual patterns, requiring them to link sensory input with motor action (licking a spout for a reward).

  • The study found no single brain region responsible for decision-making; instead, neurons across the brain sparsely integrate sensory evidence to trigger actions.

  • Comparing trained and naive mice, researchers discovered that learning enables broader integration of sensory information across the brain.

Why It Matters: This research could help improve artificial intelligence by offering insights into how distributed neural networks can be designed to mimic the brain’s decision-making processes.

Recommended Newsletter

Must-Read AI Healthcare News This Week

Swiss surgeons performed a successful remote endoscopy on a pig in Hong Kong, using a video game controller over 9,300 km away.

Medicare Advantage care denials increased +50% between 2022-2023, with AI algorithms blamed for increasing inappropriate denials, adding significant costs and burdens to the healthcare system, says AHA.

Harvard scientists develop a 3D organoid method to generate functional muscle stem cells in vitro, advancing treatments for neuromuscular disorders and enabling large-scale muscle repair research.

Hippocratic AI and Adtalem are creating a curriculum to train nurses on AI integration in healthcare, covering AI basics, ethical considerations, and clinical applications, launching in Spring 2025.

Chai Discovery, backed by OpenAI and Thrive Capital, has raised $30M to develop Chai-1, an advanced AI model for molecular structure prediction (an alternative to DeepMind’s AlphaFold).

AstraZeneca has developed MILTON, an AI that analyses patient test results collected by GPs to predict with high confidence a disease diagnosis years later.

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